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1

A brief history of antibiotics and select advances in their synthesis

Nicolaou, Kyriacos C, Rigol, Stephan

Journal:

The Journal of Antibiotics

Year:

2017

Language:

english

File:

PDF, 5.39 MB

english, 2017

2

Chemie und Biologie von Taxol

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Wei-Min Dai, Rodney Kiplin Guy

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 4.65 MB

german, 1994

3

Chemistry and Biology of Taxol

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Wei-Min Dai, Mr. Rodney Kiplin Guy

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 2.82 MB

english, 1994

4

Total Synthesis of Zaragozic Acid A/Squalestatin S1

Prof. Dr. Kyriacos C. Nicolaou, Alan Nadin, James E. Leresche, Eddy W. Yue, Susan La Greca

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 264 KB

english, 1994

5

The Conquest of Taxol

Prof. Dr. Kyriacos C. Nicolaou, Rodney K. Guy

Journal:

Angewandte Chemie International Edition

Year:

1995

Language:

english

File:

PDF, 1.62 MB

english, 1995

6

Book Review: Robert Burns Woodward Architect and Artist in the World of Molecules. Edited by Otto T. Benfey and Peter J. T Morris

Kyriacos C. Nicolaou

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

7

A short synthetic route to prostaglandins utilizing position-selective epoxide opening by the vinyl gilman reagent

E.J. Corey, Kyriacos C. Nicolaou, David J. Beames

Journal:

Tetrahedron Letters

Year:

1974

Language:

english

File:

PDF, 134 KB

english, 1974

8

Efficient and mild lactonization method for the synthesis of macrolides

Corey, E. J., Nicolaou, Kyriacos C.

Journal:

Journal of the American Chemical Society

Year:

1974

Language:

english

File:

PDF, 417 KB

english, 1974

9

Additions of chlorosulfonyl isocyanate and sulfenyl halides to benzvalene

Katz, Thomas J., Nicolaou, Kyriacos C.

Journal:

Journal of the American Chemical Society

Year:

1974

Language:

english

File:

PDF, 254 KB

english, 1974

10

ChemInform Abstract: Synthesis and Biological Evaluation of New Paclitaxel Analogues and Discovery of Potent Antitumor Agents.

Nicolaou, Kyriacos C., Valiulin, Roman A.

Journal:

Year:

2013

File:

PDF, 26 KB

2013

11

Total Synthesis in Search of Potent Antibody–Drug Conjugate Payloads. From the Fundamentals to the Translational

Nicolaou, Kyriacos C., Rigol, Stephan

Journal:

Accounts of Chemical Research

Year:

2018

Language:

english

File:

PDF, 5.95 MB

english, 2018

12

The Role of Organic Synthesis in the Emergence and Development of Antibody-Drug Conjugates as Targeted Cancer Therapies

Nicolaou, Kyriacos C., Rigol, Stephan

Journal:

Angewandte Chemie International Edition

Year:

2019

Language:

english

File:

PDF, 8.23 MB

english, 2019

13

Kurze und effiziente Totalsynthesen von Alkannin und Shikonin

Kyriacos C. Nicolaou, David Hepworth

Journal:

Angewandte Chemie

Year:

1998

File:

PDF, 80 KB

1998

14

Einfache Festphasensynthese von Oligosacchariden – Herstellung eines Dodecasaccharids

Kyriacos C. Nicolaou, Nobuhide Watanabe, Jim Li, Joaquín Pastor, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 148 KB

german, 1998

15

Stereoselektive Synthese des Everninomicin-A1B(A)C-Gerüsts

Kyriacos C. Nicolaou, Rosa M. Rodríguez, Helen J. Mitchell, Floris L. van Delft

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 91 KB

german, 1998

16

Einfache Zugänge zu Evernitrose und Vancosaminderivaten sowie Synthese eines Vancomycin-Modellglycosids

Kyriacos C. Nicolaou, Helen J. Mitchell, Floris L. van Delft, Frank Rübsam, Rosa M. Rodríguez

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 93 KB

german, 1998

17

Chemie und Biologie der Epothilone

Kyriacos C. Nicolaou, Frank Roschangar, Dionisios Vourloumis

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 1.51 MB

german, 1998

18

Total Synthesis and Biological Evaluation of Glycolipids Plakosides A, B and Their Analogs

Kyriacos C. Nicolaou, Jim Li, Gerhard Zenke

Journal:

Helvetica Chimica Acta

Year:

2000

Language:

english

File:

PDF, 609 KB

english, 2000

19

Ein wasserlösliches Prodrug von Taxol mit der Fähigkeit zur Selbstorganisation

Kyriacos Costa Nicolaou, Rodney Kiplin Guy, Prof. Dr. Emmanuel Nicolaou Pitsinos, Wolfgang Wrasidlo

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 822 KB

german, 1994

20

Synthese von C-2-analogen Taxolen

Prof. Dr. Kyriacos Costa Nicolaou, E. A. Couladouros, P. G. Nantermet, J. Renaud, Rodney Kiplin Guy, Wolfgang Wrasidlo

Journal:

Angewandte Chemie

Year:

1994

Language:

german

File:

PDF, 365 KB

german, 1994

21

Saragossasäure A/Squalestatin S1: synthetische und retrosynthetische Untersuchungen

Prof. Dr. Kyriacos Costa Nicolaou, Eddy W. Yue, Yoshimitsu Naniwa, Francesco De Riccardis, Alan Nadin, James E. Leresche, Susan La Greca, Zhen Yang

Journal:

Angewandte Chemie

Year:

1994

File:

PDF, 487 KB

1994

22

Totalsynthese von Saragossasäure A/Squalestatin S1

Prof. Dr. Kyriacos Costa Nicolaou, Alan Nadin, James E. Leresche, Eddy W. Yue, Susan La Greca

Journal:

Angewandte Chemie

Year:

1994

File:

PDF, 257 KB

1994

23

Synthese des ersten vollständig funktionalisierten Gerüstes der Saragossasäuren/Squalestatine

Prof. Dr. Kyriacos Costa Nicolaou, Alan Nadin, James E. Leresche, Susan La Greca, Tatsuo Tsuri, Eddy W. Yue, Zhen Yang

Journal:

Angewandte Chemie

Year:

1994

File:

PDF, 511 KB

1994

24

DNA-Kohlenhydrat-Erkennung: Design und Synthese eines an eine DNA-Sequenz aus acht Basen selektiv bindenden Oligosaccharids

Prof. Dr. Kyriacos Costa Nicolaou, Keiichi Ajito, Hironori Komatsu, Brian M. Smith, Tianhu Li, Miles G. Egan, Luigi Gomez-Paloma

Journal:

Angewandte Chemie

Year:

1995

File:

PDF, 387 KB

1995

25

Die Eroberung von Taxol

Prof. Dr. Kyriacos C. Nicolaou, Rodney K. Guy

Journal:

Angewandte Chemie

Year:

1995

Language:

german

File:

PDF, 1.28 MB

german, 1995

26

Die Totalsynthese von Brevetoxin B – eine zwölf Jahre währende Odyssee in der organischen Synthese

Prof. Dr. Kyriacos Costa Nicolaou

Journal:

Angewandte Chemie

Year:

1996

Language:

german

File:

PDF, 2.36 MB

german, 1996

27

Kupfer(I)-unterstützte Stille-Kupplung von α-stannylsubstituierten Enolethern mit Enoltriflaten: Aufbau von komplexen Polyethergerüsten

Prof. Dr. Kyriacos Costa Nicolaou, Mitsunobu Sato, Neil D. Miller, Janet L. Gunzner, Johanne Renaud, Edouard Untersteller

Journal:

Angewandte Chemie

Year:

1996

File:

PDF, 496 KB

1996

28

Chemie und Biologie der Saragossasäuren/Squalestatine

Dr. Alan Nadin, Prof. Dr. Kyriacos Costa Nicolaou

Journal:

Angewandte Chemie

Year:

1996

Language:

german

File:

PDF, 3.35 MB

german, 1996

29

Totalsynthese von Epothilon A durch Makrolactonisierung

Prof. Dr. Kyriacos C. Nicolaou, Dr. Francisco Sarabia, Dr. Sacha Ninkovic, Dr. Zhen Yang

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 286 KB

1997

30

Synthese des bicyclischen Gerüstes von CP-225,917 und CP-263,114 durch intramolekulare Diels-Alder-Reaktion

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Michael W. Härter, Dr. Lee Boulton, Dr. Bernd Jandeleit

Journal:

Angewandte Chemie

Year:

1997

Language:

german

File:

PDF, 356 KB

german, 1997

31

Eine neuartige Strategie zum Aufbau des Vancomycin-Biarylringsystems

Prof. Dr. Kyriacos C. Nicolaou, Dr. Xin-Jie Chu, Dr. Joshi M. Ramanjulu, Dr. Swaminathan Natarajan, Dr. Stefan Bräse, Dr. Frank Rübsam, Christopher N. C. Boddy

Journal:

Angewandte Chemie

Year:

1997

Language:

german

File:

PDF, 245 KB

german, 1997

32

Gezielt entworfene Epothilone: kombinatorische Synthese, Induktion der Tubulin-Polymerisation und cytotoxische Wirkung gegen taxolresistente Tumorzellen

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Dionisios Vourloumis, Dr. Tianhu Li, Dr. Joaquin Pastor, Nicolas Winssinger, Yun He, Dr. Sacha Ninkovic, Dr. Francisco Sarabia, Dr. Hans Vallberg, Dr. Frank Rosc

Journal:

Angewandte Chemie

Year:

1997

Language:

german

File:

PDF, 728 KB

german, 1997

33

Totalsynthese von Eleutherobin

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Floris Van Delft, Dr. Takashi Ohshima, Dr. Dionisios Vourloumis, Dr. Jinyou Xu, Dr. Seijiro Hosokawa, Jeffrey Pfefferkorn, Dr. Sanghee Kim, Dr. Tianhu Li

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 526 KB

1997

34

Ein neuartiger Zugang zum zentralen Gerüst von CP-225,917 und CP-263,114

Prof. Dr. Kyriacos C. Nicolaou, Dr. Maarten H. D. Postema, Dr. Neil D. Miller, Dr. Guang Yang

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 487 KB

1997

35

Synthesis of C-2 Taxol Analogues

Prof. Dr. Kyriacos Costa Nicolaou, Elias A. Couladouros, Phillipe G. Nantermet, Joanne Renaud, Rodney Kiplin Guy, Wolfgang Wrasidlo

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 331 KB

english, 1994

36

A Water-Soluble Prodrug of Taxol with Self-Assembling Properties

Prof. Dr. Kyriacos Costa Nicolaou, Rodney Kiplin Guy, Emmanuel Nicolauo Pitsinos, Wolfgang Wrasidlo

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 747 KB

english, 1994

37

Synthesis of the First Fully Functionalized Core of the Zaragozic Acids/Squalestatins

Prof. Kyriacos C. Nicolaou, Alan Nadin, James E. Leresche, Susan La Greca, Tatsuo Tsuri, Eddy W. Yue, Zhen Yang

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 464 KB

english, 1994

38

Zaragozic Acid A/Squalestatin S1: Synthetic and Retrosynthetic Studies

Prof. Kyriacos C. Nicolaou, Eddy W. Yue, Yoshimitsu Naniwa, Francesco De Riccardis, Alan Nadin, James E. Leresche, Susan La Greca, Zhen Yang

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 460 KB

english, 1994

39

The Total Synthesis of Brevetoxin B: A Twelve-Year Odyssey in Organic Synthesis

Prof. Dr. Kyriacos Costa Nicolaou

Journal:

Angewandte Chemie International Edition

Year:

1996

Language:

english

File:

PDF, 9.24 MB

english, 1996

40

Identification of Distinct Thiopeptide-Antibiotic Precursor Lead Compounds Using Translation Machinery Assays

Agata L. Starosta, Haiou Qin, Aleksandra Mikolajka, Gulice Y.C. Leung, Kathrin Schwinghammer, Kyriacos C. Nicolaou, David Y.-K. Chen, Barry S. Cooperman, Daniel N. Wilson

Journal:

Chemistry & Biology

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

41

Studies towards the synthesis of esperamicinone

David A. Clark, Francesco de Riccardis, Kyriacos C. Nicolaou

Journal:

Year:

1994

Language:

english

File:

PDF, 2.71 MB

english, 1994

42

Total synthesis of globotriaosylceramide (Gb3) and lysoglobotriaosylceramide (lysoGb3)

Kyriacos C. Nicolaou, Thomas J. Caulfield, Hideaki Katoaka

Journal:

Carbohydrate Research

Year:

1990

Language:

english

File:

PDF, 1.12 MB

english, 1990

43

Anti-thromboxane A2 actions of pinane thromboxane A2 derivatives

David M. Roth, Allan M. Lefer, J. Bryan Smith, Kyriacos C. Nicolaou

Journal:

Prostaglandins, Leukotrienes and Medicine

Year:

1982

Language:

english

File:

PDF, 325 KB

english, 1982

44

Total synthesis of amphoteronolide B

Nicolaou, Kyriacos C., Daines, R. A., Chakraborty, T. K.

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 353 KB

english, 1987

45

Total synthesis of amphoteronolide B and amphotericin B. 2. Total synthesis of amphoteronolide B

Nicolaou, Kyriacos C., Daines, R. A., Chakraborty, T. K., Ogawa, Y.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 2.11 MB

english, 1988

46

Studies on the protective effect of prostacyclin in acute myocardial ischemia

Martin L. Ogletree, Allan M. Lefer, J. Bryan Smith, Kyriacos C. Nicolaou

Journal:

European Journal of Pharmacology

Year:

1979

Language:

english

File:

PDF, 740 KB

english, 1979

47

Selective inhibition of 5-lipoxygenase by 5,6-methanoleukotriene A4, a stable analogue of leukotriene A4

Yasuko Koshishara, Sei-itsu Murota, Nicos A. Petasis, Kyriacos C. Nicolaou

Journal:

Year:

1982

Language:

english

File:

PDF, 318 KB

english, 1982

48

Responsiveness of platelets and coronary arteries from different species to synthetic thromboxane and prostaglandin endoperoxide analogues

Sandra E. Burke, Allan M. Lefer, Kyriacos C. Nicolaou, Gordon M. Smith, J. Bryan Smith

Journal:

British Journal of Pharmacology

Year:

1983

Language:

english

File:

PDF, 1013 KB

english, 1983

49

Stereocontrolled construction of key building blocks for the total synthesis of amphoteronolide B and amphotericin B

Nicolaou, Kyriacos C., Daines, R. A., Uenishi, J., Li, W. S., Papahatjis, D. P., Chakraborty, T. K.

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 516 KB

english, 1987

50

Spasmogenic effects of the anti-fertility agent, zoapatanol

J.Bryan Smith, Edward F. Smith III, Allan M. Lefer, Kyriacos C. Nicolaou

Journal:

Year:

1981

Language:

english

File:

PDF, 173 KB

english, 1981